Following Cathie Wood: Continued to significantly increase stake in SpaceX by over 150,000 shares, while reducing holdings in semiconductor leader AMD

On Monday, all three major U.S. stock indexes closed lower: the S&P 500 ended at 7,515.34, down 0.79%; the Nasdaq closed at 25,873.18, falling 1.55%; and the Dow Jones Industrial Average declined slightly by 0.26% to 52,498.64. Amid this market correction, Cathie Wood continued to demonstrate strong conviction in disruptive innovation sectors.

On Monday, Cathie Wood substantially added to emerging nuclear energy stocks, deepened her investments in gene therapy, and moderately trimmed some tech holdings to reallocate capital.

Buying focus: Revival of nuclear energy and cutting-edge gene therapies

Cathie Wood made a large-scale purchase$X-Energy (XE.US)$reaching 545,000 shares, which likely reflects her strong bullish view on next-generation nuclear technology. X-Energy, a leader in high-temperature gas-cooled reactor technology, is developing modular small reactors—a key direction in the global energy transition. Additionally, she increased holdings in$Oklo Inc (OKLO.US)$by over 100,000 shares, further solidifying her allocation in the advanced nuclear energy space.

Meanwhile, she also added to $SpaceX (SPCX.US)$ Increased holdings by over 150,000 shares in a national defense security company $Kratos Defense & Security Solutions (KTOS.US)$ Added 92,800 shares, signaling confidence in low-Earth-orbit satellite and modern drone defense technologies.

In the precision medicine space, Cathie Wood significantly increased her stakes$Prime Medicine (PRME.US)$by nearly 247,000 shares and$Beam Therapeutics (BEAM.US)$over 80,000 shares, respectively—both are frontier companies in gene editing and gene therapy. Prime Medicine's Prime Editing technology is considered a breakthrough innovation for next-generation gene therapy, while Beam's base editing platform holds significant potential for treating genetic diseases.

Notably, Cathie Wood also made substantial purchases of$Recursion Pharmaceuticals (RXRX.US)$over 130,000 shares in a company that leverages an AI-driven drug discovery platform, perfectly aligning with ARK’s investment thesis on the convergence of 'AI + biotech.'

In autonomous driving, ARK bought into multiple self-driving stocks at once, including $Kodiak AI (KDK.US)$ 71,700 shares in a company specializing in autonomous trucks, as well as $Pony AI (PONY.US)$ 49,500 shares in a leading Chinese firm focused on robotaxis. This suggests ARK may believe autonomous driving technology has moved beyond the R&D phase and is poised for large-scale commercial deployment.

In the blockchain and digital assets space, increased holdings$Securitize (SECZ.US)$by 340,000 shares, possibly reflecting optimism about its prospects in digital securities.

Selling activity: Tech sector rebalancing and concentration management

On the selling side, Cathie Wood reduced her position in$Personalis (PSNL.US)$by nearly 277,000 shares, likely due to intense competition facing the company in the oncology genomics testing space. She also trimmed positions in$Twist Bioscience (TWST.US)$and$10x Genomics (TXG.US)$, potentially reflecting a selective allocation strategy within the biotech sector.

Most notably, she cut holdings in$Advanced Micro Devices (AMD.US)$by over 40,000 shares, possibly out of caution regarding short-term volatility in the semiconductor industry or to free up capital for emerging energy investments. Additionally, she reduced stakes in$Roku Inc (ROKU.US)$and$Baidu (BIDU.US)$, which may indicate a tactical adjustment in her outlook on streaming media and Chinese ADRs.

Furthermore, she also trimmed her position in agricultural machinery giant $Deere (DE.US)$ Over 20,000 shares. This aligns with ARK's investment discipline of divesting from traditional cyclical sectors and focusing purely on technological innovation.

Overall, Cathie Wood’s latest moves demonstrate a clear strategic shift—away from traditional tech stocks and toward the energy transition and cutting-edge medical technologies—reflecting her forward-looking assessment of long-term disruptive innovation trends.

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