Eastern Time on Tuesday, the three major U.S. stock indexes closed mixed; chip stocks generally retreated, and weakness in tech stocks weighed on the Nasdaq, causing it to lead declines. However, the healthcare sector remained solid due to Humana’s strong performance, which also helped the Dow maintain its upward momentum.
Against this backdrop, 'Woodie' (Cathie Wood) has continued to increase her position in the gene-editing leader $Intellia Therapeutics (NTLA.US)$ ; while on the sell side, she targeted synthetic biology stocks that had already reached high gains recently $Twist Bioscience (TWST.US)$ , as well as the transplantation diagnostic target $CareDx (CDNA.US)$ Take profit at high levels.

Buy direction: Maintain gene editing layout
– Aggressively bought $Intellia Therapeutics (NTLA.US)$ 40,000 shares.NTLA, a gene-editing target with extremely high weighting in the ARK portfolio, is currently on the eve of releasing critical clinical data. The market expects its CRISPR in vivo editing technology to achieve landmark progress in treating genetic diseases.
– Slightly increase holdings simultaneously $Natera (NTRA.US)$ 4,310 shares.NTRA continues to consolidate its leading position in the field of oncology liquid biopsies. The company's recently announced earnings show that its testing volume growth has exceeded expectations.
Sell direction: Take profit at high levels
– Reduce holdings $Twist Bioscience (TWST.US)$56,400 shares.TWST has been the star of the recent synthetic biology sector, with its stock price recording an astonishing increase over the past few weeks. ARK's reduction in holdings does not indicate a lack of confidence in TWST’s technology but rather represents a typical 'rotation at highs.' TWST still faces pressure on gross margins and risks from long-term R&D investments. ARK chose to cash out at this high point to reallocate liquidity, transferring funds precisely to NTLA, which appears to have better 'value for money.'
– Continued reduction $CareDx (CDNA.US)$ of 14,400 shares.The continued reduction in CareDx reflects ARK's reassessment of the competitive landscape in the transplant care space. With increasing pricing pressures in the industry, this once highly anticipated diagnostics company is gradually losing its weight in ARK's core portfolio.
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