Tracking Cathie Wood: Increasing positions in nuclear energy and precision medicine, significantly reducing holdings in Roblox and genomics targets

On Thursday, August 20, the three major US stock indices closed lower collectively. The S&P 500 fell 0.87% to close at 7,641.16, the Nasdaq dropped 1.00% to 26,067.17, and the Dow Jones led the decline with a 1.32% drop, closing at 52,759.21. The overall market was under pressure, with risk sentiment leaning cautious.

Against the backdrop of a broad market downturn, ARK Invest increased its holdings in frontier sectors such as nuclear energy, early cancer screening, and on-chain finance on the day. Meanwhile, it trimmed positions in certain platform consumer and genomics stocks. The overall strategy points to a structural reallocation toward core assets of disruptive innovation.

Symbols

Buy Direction: Continue to position in nuclear energy, precision medicine, and

$BWX Technologies (BWXT.US)$ Increased holdings by 47,092 shares. BWXT is a core supplier of small modular reactors (SMRs) and nuclear propulsion systems. Recently, as countries accelerate their energy security strategies and power demand from AI data centers surges, the investment thesis for nuclear infrastructure has become increasingly clear. ARK's addition to its position at this juncture may reflect confidence in BWXT's certain beneficiary status in the new wave of nuclear renaissance.

$Freenome (FRNM.US)$ Increased holdings by 46,141 shares. Freenome is a biotechnology company deeply engaged in liquid biopsy and early cancer screening, with its technological approach highly aligned with ARK's long-promoted core theme of the 'Precision Medicine Revolution.' This significant increase in holdings may reflect ARK's continued optimism regarding its technological progress or commercialization process.

$Securitize (SECZ.US)$ Increased holdings by 14,751 shares. Securitize is one of the leaders in the tokenization of real-world assets (RWA), focusing on compliant on-chain securities issuance and circulation. Amid the broader trend of institutional investors accelerating their adoption of on-chain financial infrastructure, ARK's continued accumulation of this asset may aim to strengthen its core allocation in the blockchain finance sector.

$Futu Holdings Ltd (FUTU.US)$ Increased holdings by 10,577 shares. Futu Holdings Ltd, a leading fintech company in securities trading and wealth management, announced its financial results for the second quarter of 2026 on August 20. Total revenue reached HK$7.2 billion (approximately US$918 million), representing a year-over-year growth of 35.6%. The number of registered users for Futu's Futubull and moomoo apps reached 31.25 million, and the number of accounts stood at 6.64 million, representing year-over-year increases of 15% and 27%, respectively.

Sell direction: Rebalancing positions in platform consumption and genomics

$Roblox (RBLX.US)$ Reduced holdings by 163,494 shares, marking the largest single reduction of the day. As a metaverse and gamified social platform, Roblox has recently faced slowing user growth and monetization pressure. ARK's significant reduction in its position may stem from considerations to lower concentration in platform consumption assets and reallocate capital to sectors with higher certainty.

$10x Genomics (TXG.US)$ Reduced holdings by 65,922 shares. 10x Genomics is deeply involved in spatial omics and single-cell sequencing, but its recent performance has been under pressure, with commercialization progress falling short of expectations. ARK's adjustment of its position is speculated to be active management based on industry rotation rhythms, rather than a denial of its long-term technological prospects.

$Shopify (SHOP.US)$ Reduced holdings by 34,835 shares. Shopify is a long-held e-commerce infrastructure asset for ARK. The moderate scale of this reduction is more likely a routine portfolio rebalancing operation to free up capital for the aforementioned increases in emerging sectors.

$Brera Holdings (SLMT.US)$ Reduced holdings by 9,930 shares,$Deere (DE.US)$ Reduced holdings by 2,528 shares,$AtaiBeckley (ATAI.US)$ Reduced holdings by 360 shares. The aforementioned three reductions were relatively small in scale and are more likely part of routine portfolio optimization adjustments to maintain the structural balance of the overall investment portfolio.

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