Tracking Cathie Wood: Continues to add over 170,000 shares of SpaceX, while reducing biotech stock ATAI by over 710,000 shares

U.S. stock markets traded in a volatile and corrective pattern on Monday. The S&P 500 fell 0.19% to close at 7,443.28, the Nasdaq slipped slightly by 0.05% to 25,508.07, and the Dow Jones Industrial Average dropped 0.59% to 51,839.26. Against a backdrop of relatively cautious market sentiment, investor attitudes toward tech stocks have become increasingly divergent.

On Monday, Cathie Wood's trades significantly increased exposure to precision medicine and AI infrastructure while adjusting positions in e-commerce platforms and cloud computing stocks, reflecting her ongoing optimization of the disruptive innovation portfolio.

Buy-side focus: Targeting gene editing and AI infrastructure to position for next-generation healthcare technologies

ARK's largest single-day purchase$Prime Medicine (PRME.US)$491,418 shares—this gene-editing company specializes in Prime Editing technology, regarded as the next-generation gene-editing tool following CRISPR. She also substantially increased her stake in$COMPASS Pathways (CMPS.US)$238,048 shares—this company leads in psychedelic-based treatments for depression, aligning with ARK’s investment thesis on the precision medicine revolution.

In AI infrastructure, Cathie Wood added to her position in$Tempus AI (TEM.US)$188,785 shares—this company leverages AI to analyze cancer genomic data, providing decision support for personalized therapies.

She also increased holdings in$SpaceX (SPCX.US)$170,634 shares and$Archer Aviation (ACHR.US)$121,300 shares, signaling continued confidence in the space economy and urban air mobility.

Notably, ARK also added to its position in autonomous driving plays:$Pony AI (PONY.US)$90,778 shares and$WeRide (WRD.US)$54,278 shares, as well as blockchain infrastructure holdings$Securitize (SECZ.US)$83,233 shares, reflecting its comprehensive positioning across diversified disruptive technologies.

Selling activity: Adjusting biotech and traditional tech allocations to optimize the portfolio

On the sell side, ARK significantly reduced its stake in$AtaiBeckley (ATAI.US)$719,543 shares, possibly related to the company's clinical progress in mental health treatments falling short of expectations. It also trimmed$Strata Critical Medical (SRTA.US)$228,964 shares and$Shopify (SHOP.US)$203,352 shares, the latter potentially reflecting a reassessment of the e-commerce platform's valuation.

In traditional tech stocks, Cathie Wood reduced her holdings in$Baidu (BIDU.US)$48,836 shares and$Robinhood (HOOD.US)$41,322 shares and$Snowflake (SNOW.US)$14,684 shares are among the targeted holdings. Particularly notable is$Advanced Micro Devices (AMD.US)$the reduction of 8,129 shares, which may reflect the view that semiconductor stocks’ short-term valuations have already fully priced in fundamental expectations.

This series of moves indicates that ARK is engaging in refined portfolio management—trimming weaker positions while reallocating capital to emerging sectors with greater disruptive innovation potential—demonstrating its deep insight into long-term technology trends and forward-looking positioning.

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